Molecule Steward Lead - Small Molecules

Position Summary

You will lead molecule stewardship for small molecule programs across development and manufacturing, partnering with discovery, process development, analytics, regulatory, manufacturing and external suppliers. This role offers visible influence across program lifecycles, strong growth opportunities, and the chance to help GSK unite science, technology and talent to advance patient impact.

Responsibilities

• Lead technical stewardship for a portfolio of small molecule programs from candidate selection through commercial lifecycle.
• Define and maintain product control strategies, lifecycle plans and technical deliverables.
• Coordinate cross‑functional teams on technology transfers, process performance qualification and ongoing process verification.
• Oversee technical risk assessments and deliver mitigation plans for quality, supply and regulatory readiness.
• Provide hands‑on technical leadership for investigations, troubleshooting and major change programs across sites and suppliers.
• Mentor and develop the molecule stewardship team and build strong relationships across the network.
• Own end‑to‑end technical strategy and decision points for assigned small molecule assets.
• Translate scientific and analytical data into clear, actionable guidance for program teams and stakeholders.
• Ensure data integrity, documentation and evidence support for regulatory submissions and inspections.
• Drive alignment across sites, contract manufacturers and internal teams to ensure consistent product performance.
• Lead Product Technical Lifecycle Team activities and yearly robustness reviews to identify and resolve risks.
• Share best practices for characterization, stability strategies and analytical approaches to improve product robustness.

Basic Qualifications

• Bachelor’s degree in chemistry, pharmaceutical sciences, chemical engineering or related field. Advanced degree preferred.
• At least 8 years’ experience in small molecule development, analytical development, process development or related area.
• Demonstrated experience in molecule stewardship, technology transfer or product lifecycle management for small molecules.
• Experience leading cross‑functional teams and making technical decisions in a matrix environment.
• Knowledge of global regulatory expectations for pharmaceutical development, manufacturing and quality.
• Experience managing technical aspects of investigations, deviations and corrective actions.

Preferred Qualifications

• Master’s or PhD in a relevant discipline.
• Direct experience with technology transfer to multiple sites and with contract manufacturing organizations.
• Experience designing stability programs and analytical characterization strategies for small molecules.
• Familiarity with risk‑based approaches and project management tools.
• Proven track record developing technical talent and leading diverse teams.
• Comfortable working across time zones and with cross‑cultural, matrixed teams.

Key benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. The U.S. base salary range for this position is $200,250–$333,750, with additional annual bonus and eligibility to participate in a long‑term incentive program.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.