Molecular architecture of type 2 topoisomerase chromatin complexes
We are pleased to invite highly motivated postdoctoral fellows to join our team in the Integrated Structural Biology Department at IGBMC (Institute of Genetics and Molecular and Cellular Biology), University of Strasbourg, France (igbmc.fr: ISB dept, Team Regulation of DNA topology).
Our laboratory focuses on elucidating the structural and molecular mechanisms of type II DNA topoisomerase (Top2) complexes using an integrated approach combining biochemistry, molecular biology, cryo‑electron microscopy (cryo‑EM), and mass spectrometry. Top2. We are seeking outstanding postdoctoral researchers to contribute to two main research directions: (1) the structural characterization of Top2 nucleoprotein complexes involved in the regulation of DNA topology, and (2) the identification and functional analysis of interaction networks within human Top2 chromatin‑associated complexes. Candidates should hold a Ph.D. in a biology‑related discipline and demonstrate strong motivation for collaborative and interdisciplinary research. Expertise in one or more of the following areas—biochemistry, cryo‑EM, or mass spectrometry—will be considered a strong asset.
Who can apply?
Researchers of any nationality who:
- Have completed a PhD or will complete it at the date of the call deadline (September 2026).
- Have a maximum of 8 years full‑time equivalent experience in research at the time of the call deadline.
- Have not resided or carried out their main activity (work, studies, etc.) in France for more than 12 months in the 3 years immediately prior to the call deadline.
Beware that applicants who have applied to the MSCA Postdoctoral Fellowship 2025 call and received an evaluation below 80% are not eligible for an application in 2026.
How to apply?
We encourage all motivated and eligible postdoctoral researchers to send their expressions of interest to the supervisor’s e-mail address before 24th April 2026.
Your application shall include:
- a CV (5 pages max)
- a cover letter outlining your research background and its synergies with the supervisor’s field and/or the proposed research topic.
Estimated timetable:
- Deadline for sending an expression of interest: 24th April 2026
- Selection of the applicant: May 2026 at the latest