Lead researcher position in Biomaterials and Bioengineering

Overview

This project aims to develop innovative strategies for generating osteogenic grafts for the regeneration of congenital or acquired bone defects. The approach is based on endochondral ossification to reproduce key stages of bone development, improving graft vascularization, integration, and functionality. The objective is to utilize readily available human cells (particularly those derived from adipose tissue or other mesenchymal sources) and combine them with instructive biomaterials to direct differentiation toward a chondrogenic and then an osteogenic phenotype. Attention is given to designing microenvironments that combine structural supports, biochemical signals (growth factors, morphogens), and potentially biophysical stimuli (mechanical, electrical, or electromagnetic) to optimize the robustness and reproducibility of the regenerative process. Advanced biofabrication approaches, such as 3D bioprinting and tailored bio-inks, enable control over graft architecture and the spatial distribution of cells and bioactive signals. This program is part of a strong translational dynamic with evaluation in relevant preclinical models of bone defects and close collaboration with clinical partners of the laboratory.

Responsibilities

• Involvement in the Biomaterials Master’s degree program organized in 2 courses within the University of Strasbourg: Biomaterials and Bioengineering of Health and Intelligence in Health Data (master’s level M1 and M2).
• Supervision of the Unit\'s student interns (Bachelor\'s, Master\'s, Engineering levels) and supervision of doctoral students.

Notes

The description provides project goals and supervisory responsibilities but does not specify formal qualifications or entry requirements for the candidate. Consider adding explicit required or preferred qualifications, experience, and skills to complete the job description.