Laboratory Technician

I am currently partnered with an exciting Small Biotech in Paris ready to tackle 2026 and they need a Lab Technician to initiate their success, if you believe you are the right fit please check the Job Description and apply now!

We are seeking an experienced technician in cell culture and/or sequencing to help generate a large-scale perturbation dataset designed for machine learning applications. In this role, you will establish and maintain primary and iPSC cell lines, treat them with antisense oligonucleotides, extract RNA, prepare long-read sequencing libraries, load flow cells, and operate long-read sequencing platforms. You will work closely with an interdisciplinary team of biologists and machine learning engineers, collaborating between the lab and computational teams to test a variety of compounds and refine experimental approaches.

The ideal candidate will have extensive hands-on experience in 10x Genomics, RNA sequencing library preparation, a meticulous and detail-oriented approach to laboratory work, and the ability to adapt quickly in a dynamic environment. Strong communication skills and a collaborative mindset are essential. Prior experience with long-read sequencing technologies is highly advantageous

Salary range: Depending on Experience

Language: Fluent in English

Location: Paris

Must-have experience and skills

· Working on human sample (dissociation/extraction of cells or nuclei) and using microscopy (fluorescence).

· Molecular biology: library preparation for NGS, bioanalyzer or Tapestation, DNA and RNA extraction, qPCR, RT-PCR.

· Experience in single-cell experiments 10x Genomics and robot dispensers (EpiMotion, Mosquito …) would be be particularly appreciated.

· Familiarity with quality standards (ISO 15189, ISO 17025, GLP, etc.) would be be particularly appreciated.

Your daily task will be to generate single-cell data from FFPE samples under the supervision of a laboratory engineer. You should be comfortable with routine laboratory work.

· Carry out and ensure the completion of single cell omics data generation pipelines in a standardized fashion way:

o Organize human sample reception (Frozen and/or FFPE)

o Perform librairies preparation (10X genomics)

o Implement PCR/qPCR techniques, purification, dosage and quality control

o Prepare and launch sequencing runs (NGS-Illumina)

o Report results autonomously and clearly (Labguru)

· Assist the research team in development and validation of new multi-omics experiments.

· Assist in monitoring stocks, orders and equipment maintenance.

Education level

· BTS or DUT/BUT (Bioanalyses; Biotechnologies; Biological engineering or related disciplines).

· At least two-years of proven experience in Molecular Biology.

· Experience on a genomics and/or sequencing platform.

Non technical skills

· Comfortable with routine laboratory work

· Good level in English (reading, writing and speaking);

· Excellent communications and team working skills;

· Rigorous; high standards of integrity, accuracy and attention to details;

· Adaptable, organized, rigorous and results-oriented.

• · Strong team spirit, taking initiatives to help out others when neededMS)