Engineer in organoid development (F/M) (F/H)

The Curie Institute Research Center

The “Institut Curie” is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness.

The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

Missions

The Preclinical Investigation Laboratory (LIP)

The preclinical investigation laboratory (LIP) is specialised in the development of preclinical cancer models, PDX and organoids for research and clinical cancer projects. The LIP is made up of a team dedicated to PDXs and another team focused on organoid development from patients or PDX models. The laboratory is actively involved in numerous collaborative projects at a national and international level that include PDX and organoid use.

The candidate will take part in managing a bank of organoid models generated from patient derived organoids (PDO) or PDX (PDXO). They will be responsible for cultivating and amplifying the organoids, generating samples for molecular characterisation and evaluating the efficacy of anticancer therapies in vitro.

• Participation in the development of organoid models from patient samples or PDX for different cancer types and different research projects
• Amplification and upkeep of organoids
• Management of frozen and fixed samples for molecular characterization and phenotyping of organoids
• Monotherapy and combination chemotherapy tests
• Optimisation of experimental protocols to ensure the success of experiments

Training and experience required

• Cellular biology qualification
• Mastering of cellular culture techniques
• Professional experience in the domain of organoids or 3D culture

Skills required

• Able to work as part of a team and work simultaneously on different projects

All our opportunities are open to people with disabilities

Contract information

Type of contract : Fixed-term contract

Duration : 6 months

Working time : full time

Remuneration : according to the current grids

Benefits : Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance

Location of the position : Paris

Contact

Please send your CV, letter of motivation and 2 references

Institut Curie is an inclusive, equal opportunity employer

and is dedicated to the highest standards of research integrity.