Clinical Trial Manager - Sponsor dedicated - Based in Rueil Malmaison

Clinical Trial Manager - Sponsor dedicated - Based in Rueil Malmaison

Updated: July 20, 2026

Location: Rueil Malmaison

Job ID:

Description

Syneos Health® is a leading fully-integrated life sciences services organization designed to accelerate customer success in drug development and commercialization.

Responsibilities

• Responsible for study oversight and delivery management (time, budget, quality) at the country level from start-up to closure.
• Serve as the main point of contact at a country level for internal and external stakeholders.
• Coordinate country cross‑functional teams and act as the primary liaison with the protocol manager and other global study team members.
• Coordinate with other internal roles in the country and site feasibility process, including proposal and validation of country study targets.
• Develop the country‑level patient recruitment strategy & risk mitigation, ensuring enrolment targets and timelines are met.
• Lead problem‑solving and resolution efforts, including risk management, contingencies, issue resolution and escalation to the appropriate stakeholder(s).
• Assess and set up vendors during the study start‑up period (locally).
• Participate in and prepare for Investigator Meetings.
• Ensure data entered in Clinical Trial Management Systems is current and complete; ensure access to eDC and vendor systems is available for the country and site personnel.
• Validate study‑related materials (protocol, ICF, patient material).
• Prepare country‑specific documents (e.g., global country‑specific amendments).
• Prepare materials for Site Initiation Visits.
• Verify and confirm local team eTMF completeness (country and site level).
• Review Site Monitoring visit reports, take action within specified timelines, and ensure appropriate documentation and escalation of issues.
• Coordinate database locks and query follow‑up, ensuring timelines are met; maintain inspection readiness of assigned trials and support Health Authority inspection and pre‑inspection activities.
• Coordinate, develop, and write Corrective Actions / Preventive Actions (CAPA), ensuring implementation for country audit‑level findings and driving CAPA review, implementation, and completion.
• Lead local study team meetings.
• Review and approve payments (based on GOA) and manage patient compensation claims (if applicable).
• Manage site relationships, including CRO related issues.
• May perform site‑closure activities, including post‑close‑out.
• May act as point of contact for sites.
• May support the preparation of submissions to and obtain approval from local Health Authorities, Ethics Committees, and other relevant instances.

Qualifications

• Thorough understanding of GCP, ICH Guidelines, and the country regulatory environment.
• In‑depth knowledge and understanding of clinical research processes, regulations, and methodology.
• Practical knowledge of a variety of medical settings and medical records management.
• Demonstrated organizational and planning skills and independent decision‑making ability.
• Experience in leading or participating as an active member of cross‑functional teams, task forces, or local and global initiatives.
• Strong organization and time‑management skills and ability to manage multiple competing priorities.
• Critical thinking and risk analysis ability.
• Strong communication skills with a strong customer focus; able to manage both internal and external clients at all organizational levels.
• Skilled in the use of technology.

Benefits

• Competitive remuneration package with excellent benefits.
• Commitment to your development and training, with the opportunity to progress your career within a market‑leading and innovative organization.
• Opportunity to work within a successful and rewarding environment.

Equal Opportunity Employer

Syneos Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, marital status, ethnicity, national origin, sex, gender, gender identity, sexual orientation, protected veteran status, disability or any other legally protected status and will not be discriminated against. If you are an individual with a disability who requires a reasonable accommodation to complete any part of the application process, including the use of this website, please contact us at